High Level of Tumor Necrosis Factor (TNF)-α is a Risk Factor for Preeclampsia
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چکیده
منابع مشابه
Association of Tumor Necrosis Factor-α (TNF-α) -308G>A and -238G>A Polymorphisms with Recurrent Pregnancy Loss Risk: A Meta-Analysis
Background: Studies have been carried out to evaluate the association of tumor necrosis factor-α (TNF-α) gene promoter region polymorphisms with recurrent pregnancy loss (RPL) risk. However, the results remain controversial and incomplete. Hence, we performed a meta-analysis to evaluate the association of TNF-α -308G>A and -238G>A polymorphisms with RPL risk. Materials and Methods: A comprehens...
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This meta-analysis of 23 eligible articles comprehensively and quantitatively evaluated the effects of tumor necrosis factor-α (TNF-α) rs1800629 and rs361525 polymorphisms on sepsis risk. We found that TNF-α rs1800629 was associated with increased sepsis risk in the overall population in four genetic models, including A vs. G (P<0.001, odds ratio (OR)=1.32), GA vs. GG (P<0.001, OR=1.46), GA+AA ...
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BACKGROUND/AIMS It has been shown that circulating tumor necrosis factor α (TNF-α) is elevated in end stage renal disease patients; however, the relationship between TNF-α and the development of infection in these patients is unknown. In this study, we investigated the association of plasma TNF-α and interleukin 6 (IL-6) with infection in peritoneal dialysis (PD) patients. We also evaluated the...
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background: preeclampsia is a disorder unique to pregnancy and has long been recognized as an important contributor of maternal and fetal morbidity and mortality. it is suggested that cytokines such as tumor necrosis factor-alpha (tnf-α) have an important role in the pathogenesis of preeclampsia and may cause generalized endothelial dysfunction. objective: the aim of this study was comparison o...
متن کاملTUMOR NECROSIS FACTOR ALPHA (TNF-a)
Tumor necrosis factor alpha (TNF, TNFSF2) is an important multifunctional cytokine that regulates inflammation, host defense, immune responses, and apoptosis. TNF exists as a membrane-bound 26kDa, type II integral membrane protein, and a 17kDa soluble homotrimeric TNF that is generated via proteolytic cleavage by TNF-a converting enzyme (TACE, ADAM17). Both the membrane-bound and soluble forms ...
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ژورنال
عنوان ژورنال: Indonesian Journal of Obstetrics and Gynecology
سال: 2016
ISSN: 2338-7335,2338-6401
DOI: 10.32771/inajog.v36i3.306